See
Genome Information for Mus musculus
Transcriptional profiling of intestinal changes in Apc Kras tumours with MYC activation and/or drug combination treatment
Overall design: Apc Kras or Apc Kras MYC mice were treated with or without a eFT508/rapamycin drug combination, then whole intestines were extracted and transcriptomic analysis performed to investigate changes occuring with MYC and/or drug treatment.
| Accession | PRJNA668925; GEO: GSE159432 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Knight JRP et al., "MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.", Cancer Discov, 2021 May;11(5):1228-1247 |
| Submission | Registration date: 13-Oct-2020
CRUK Beatson Institute |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 16 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 16 |
| GEO DataSets | 1 |