ChIP-Seq for HOXB13 in LNCaP cell line with GSK tr... (ID 627124) - BioProject

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Accession: PRJNA627124 ID: 627124

ChIP-Seq for HOXB13 in LNCaP cell line with GSK treatment and VEH control (human)

See Genome Information for Homo sapiens

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This project is a component of the Lineage-specific chromatin binding of FOXA1 is regulated by LSD1-mediated demethylation

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3 additional projects are components of the Lineage-specific chromatin binding of FOXA1 is regulated by LSD1-mediated demethylation.

93280 additional projects are related by organism.

We show in prostate cancer cells that LSD1 co-localizes with FOXA1 and active enhancer markers, and that LSD1 inhibition globally disrupts FOXA1 chromatin binding. More...

Accession	PRJNA627124; GEO: GSE148928
Data Type	Epigenomics
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Gao S et al., "Chromatin binding of FOXA1 is promoted by LSD1-mediated demethylation in prostate cancer.", Nat Genet, 2020 Oct;52(10):1011-1017
Submission	Registration date: 20-Apr-2020 University of Massachusetts Boston
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	4
Publications
PubMed	1
PMC	1
Other datasets
BioSample	4
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	608

SRA Data Details

Parameter	Value
Data volume, Gbases	4
Data volume, Mbytes	2283

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ChIP-Seq for HOXB13 in LNCaP cell line with GSK treatment and VEH control (human)

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