Continued Bcl6 expression prevents the transdiffer... (ID 596262) - BioProject

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Accession: PRJNA596262 ID: 596262

Continued Bcl6 expression prevents the transdifferentiation of established Tfh cells into Th1 cells during acute viral infection (house mouse)

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71644 additional projects are related by organism.

By using a temporally-controlled system for the ablation of Bcl6 and Cxcr5 speficially in CD4 T cells, the requirements of both factors for the maintenance of Tfh cells were investigated Overall design: Cd4-CreERT2+ mice without floxed alleles were used as controls in all experiments. More...

Accession	PRJNA596262; GEO: GSE142229
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Alterauge D et al., "Continued Bcl6 Expression Prevents the Transdifferentiation of Established Tfh Cells into Th1 Cells during Acute Viral Infection.", Cell Rep, 2020 Oct 6;33(1):108232
Submission	Registration date: 17-Dec-2019 Baumjohann Lab, Medical Clinic III, University Hospital Bonn
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	38
Publications
PubMed	1
Other datasets
BioSample	38
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	46
Data volume, Mbytes	31447

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Continued Bcl6 expression prevents the transdifferentiation of established Tfh cells into Th1 cells during acute viral infection (house mouse)

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