A pathogen-specific 4mC methyltransferase is criti... (ID 577724) - BioProject

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Accession: PRJNA577724 ID: 577724

A pathogen-specific 4mC methyltransferase is critical for epigenetic regulation and virulence of Leptospira interrogans

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312 additional projects are related by organism.

Transcriptome analysis of a mutant in an orphan methyltranferase revealed global transcriptional regulation of 100 differentially expressed genes. More...

Accession	PRJNA577724; GEO: GSE138917
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Leptospira interrogans serovar Manilae[Taxonomy ID: 214675] Bacteria; Spirochaetota; Spirochaetia; Leptospirales; Leptospiraceae; Leptospira; Leptospira interrogans; Leptospira interrogans serovar Manilae
Publications	Gaultney RA et al., "4-Methylcytosine DNA modification is critical for global epigenetic regulation and virulence in the human pathogen Leptospira interrogans.", Nucleic Acids Res, 2020 Dec 2;48(21):12102-12115
Submission	Registration date: 15-Oct-2019 Biomics Platform, Center for Technological Resources and Research, Institut Pasteur
Relevance	Unknown

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	9
Publications
PubMed	1
PMC	1
Other datasets
BioSample	9
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	4

SRA Data Details

Parameter	Value
Data volume, Gbases	8
Data volume, Mbytes	4615

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A pathogen-specific 4mC methyltransferase is critical for epigenetic regulation and virulence of Leptospira interrogans

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