See
Genome Information for Cricetulus griseus
The mechanism of action behind the increased secretion capacity of the amplified progeny of CHO cells is investigated in this study through comparative transcriptomic analysis
Overall design: The amplified DG-44 CHO cells, taken at both exponential and stationary growth phase were compared to non-amplified CHO DG-44 cells. Non-producing CHO-S samples were used as negative controls.
| Accession | PRJNA551666; GEO: GSE133511 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Cricetulus griseus[Taxonomy ID: 10029] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus; Cricetulus griseus |
| Publications | Dahodwala H et al., "Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter.", Curr Res Biotechnol, 2019 Nov;1:49-57 |
| Submission | Registration date: 28-Jun-2019
UCSD |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 24 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 24 |
| GEO DataSets | 1 |