This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA534022; GEO: GSE130119 |
| Type | Umbrella project |
| Publications | Wheeler MA et al., "MAFG-driven astrocytes promote CNS inflammation.", Nature, 2020 Feb;578(7796):593-599 |
| Submission | Registration date: 22-Apr-2019
Neurology, Brigham and Women's Hospital |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 163 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 163 |
| GEO DataSets | 13 |
MAFG-driven astrocytes promote CNS inflammation encompasses the following 12 sub-projects:
| Project Type | Number of Projects |
| Epigenomics | 2 |
BioProject
accession | Organism | Title |
|---|
| PRJNA531923 | Mus musculus | Genome-wide analysis of MAFG binding in astrocytes during EAE [ChIP-seq] (Neurology, Brigham and Women's...) | | PRJNA531924 | Mus musculus | Genome-wide analysis of DNA methylation profile in astrocytes isolated from naïve mice or EAE mice transduced with astrocyte-specific Mafg-targeting or non-targeting lentiviruses [WGBS] (Neurology, Brigham and Women's...) |
|
| Other | 1 |
BioProject
accession | Organism | Title |
|---|
| PRJNA531925 | Mus musculus | Genome-wide analysis of chromatin profile in astrocytes isolated from EAE mice transduced with astrocyte-specific Mafg-targeting or non-targeting lentiviruses [ATAC-seq] (Neurology, Brigham and Women's...) |
|
| Transcriptome or Gene expression | 9 |
BioProject
accession | Organism | Title |
|---|
| PRJNA532649 | Homo sapiens | Genome-wide analysis of the transcriptional profile of the CNS in MS patients. (Neurology, Brigham and Women's...) | | PRJNA533923 | Homo sapiens | Genome-wide analysis of the transcriptional profile of the CNS in healthy control patients. (Neurology, Brigham and Women's...) | | PRJNA534023 | Mus musculus | Genome-wide analysis of the transcriptional profile of astrocytes across EAE by CNS region in Gfap-Cre;Ribotag(f/f) mice uisng Ribotag immunoprecipitation. (Neurology, Brigham and Women's...) | | PRJNA531926 | Mus musculus | Genome-wide analysis of the transcriptional profile of the CNS during EAE in B6 mice by scRNA-seq [scRNA-seq] (Neurology, Brigham and Women's...) | | PRJNA532650 | Mus musculus | Genome-wide analysis of the transcriptional profile of astrocytes during EAE in Gfap-TdTomato mice by scRNA-seq [scRNA-seq 2] (Neurology, Brigham and Women's...) |
List all 9 'Transcriptome or Gene expression' projects...BioProject
accession | Organism | Title |
|---|
| PRJNA532649 | Homo sapiens | Genome-wide analysis of the transcriptional profile of the CNS in MS patients. (Neurology, Brigham and Women's...) | | PRJNA533923 | Homo sapiens | Genome-wide analysis of the transcriptional profile of the CNS in healthy control patients. (Neurology, Brigham and Women's...) | | PRJNA534023 | Mus musculus | Genome-wide analysis of the transcriptional profile of astrocytes across EAE by CNS region in Gfap-Cre;Ribotag(f/f) mice uisng Ribotag immunoprecipitation. (Neurology, Brigham and Women's...) | | PRJNA531926 | Mus musculus | Genome-wide analysis of the transcriptional profile of the CNS during EAE in B6 mice by scRNA-seq [scRNA-seq] (Neurology, Brigham and Women's...) | | PRJNA532650 | Mus musculus | Genome-wide analysis of the transcriptional profile of astrocytes during EAE in Gfap-TdTomato mice by scRNA-seq [scRNA-seq 2] (Neurology, Brigham and Women's...) | | PRJNA532728 | Mus musculus | Genome-wide analysis of the transcriptional profile of WT and CSF2RB astrocyte conditional KO during EAE in B6 mice [Csf2rb RNA-seq] (Neurology, Brigham and Women's...) | | PRJNA532729 | Mus musculus | Genome-wide analysis of the transcriptional profile of WT and Nfe2l2 KD astrocytes during EAE in B6 mice [Nrf2 RNA-seq] (Neurology, Brigham and Women's...) | | PRJNA559332 | Mus musculus | Genome-wide analysis of the transcriptional profile of WT and Mafg KD astrocytes during EAE in B6 mice. (Neurology, Brigham and Women's...) | | PRJNA565156 | Mus musculus | Genome-wide analysis of the transcriptional profile of IL1b/TNFa-treated and EAE astrocytes in B6 mice. (Neurology, Brigham and Women's...) |
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