See
Genome Information for Homo sapiens
Notch signaling is an evolutionarily conserved signaling pathway.NOTCH3 signaling has been shown to potentially paly an important role in luminal cell fate commitment in human breast tissue by regulating unique target genes
We overexpressed the intracellular domain of NOTCH1 (N1ICD) and NOTCH3 (N3ICD) receptor in nonmalignant human breast cell line, 184-hTerts
Overall design: 184-hTert cells were lentivirally transduced with either empty vector control, N1ICD or N3ICD. RNA was isolated for affymetrix microarray analysis
| Accession | PRJNA524386; GEO: GSE127236 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Bhat V et al., "Isolation and characterization of a new basal-like luminal progenitor in human breast tissue.", Stem Cell Res Ther, 2019 Aug 23;10(1):269 |
| Submission | Registration date: 26-Feb-2019
Immunology, University of Manitoba |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 482553 |
| Data volume, Processed Mbytes | 8 |
| Data volume, Supplementary Mbytes | 77 |