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Accession: PRJNA501791 ID: 501791

Single-cell RNA sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium (house mouse)

See Genome Information for Mus musculus
We use single-cell RNA sequencing (scRNA-seq) to explore the transcriptional changes associated with estrogen-induced dysplasia in mouse ovarian surface epithelial cells Overall design: scRNA-seq of control and estrogen-treated (100nM) mOSE cultured for 15 days. scRNA-seq was performed using the Fluidigm HT 3' RNA-seq protocol on the Fluidigm C1
AccessionPRJNA501791; GEO: GSE121957
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsVuong NH et al., "Single-cell RNA-sequencing reveals transcriptional dynamics of estrogen-induced dysplasia in the ovarian surface epithelium.", PLoS Genet, 2018 Nov;14(11):e1007788
SubmissionRegistration date: 30-Oct-2018
Cancer Therapeutics Program, Ottawa Hospital Research Institute
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments20
Publications
PubMed1
PMC1
Other datasets
BioSample20
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes72
SRA Data Details
ParameterValue
Data volume, Gbases16
Data volume, Mbytes7113

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