Hif-1alpha deletion leads to adverse treatment eff... (ID 489376) - BioProject

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Accession: PRJNA489376 ID: 489376

Hif-1alpha deletion leads to adverse treatment efficacy in a mouse model of MLL-AF9 driven AML (house mouse)

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This report explores the effect of Hif-1alpha deletion, using a conditional mouse model, together with standard chemotherapy regimen to evaluate leukemia stem cell (LSC) targeting in a murine model of MLL-AF9 driven acute myeloid leukemia (AML). More...

Accession	PRJNA489376; GEO: GSE119484
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Velasco-Hernandez T et al., "Hif-1α Deletion May Lead to Adverse Treatment Effect in a Mouse Model of MLL-AF9-Driven AML.", Stem Cell Reports, 2019 Jan 8;12(1):112-121
Submission	Registration date: 5-Sep-2018 BMC
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	4
Publications
PubMed	1
PMC	1
Other datasets
BioSample	4
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	11

SRA Data Details

Parameter	Value
Data volume, Gbases	49
Data volume, Mbytes	21543

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Hif-1alpha deletion leads to adverse treatment efficacy in a mouse model of MLL-AF9 driven AML (house mouse)

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