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Accession: PRJNA427143 ID: 427143

Systematic functional characterization of BAF mutations yields novel intra-complex synthetic lethalities [RNA-Seq] (human)

See Genome Information for Homo sapiens
Aberrations in genes coding for subunits of the BAF chromatin remodeling complex are highly abundant in human cancers. More...
AccessionPRJNA427143; GEO: GSE108388
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications
  • Schick S et al., "Systematic characterization of BAF mutations provides insights into intracomplex synthetic lethalities in human cancers.", Nat Genet, 2019 Sep;51(9):1399-1410
  • Sdelci S et al., "MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.", Nat Genet, 2019 Jun;51(6):990-998
SubmissionRegistration date: 21-Dec-2017
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments87
Publications
PubMed2
PMC2
Other datasets
BioSample87
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes13
SRA Data Details
ParameterValue
Data volume, Gbases158
Data volume, Mbytes56614

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