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Accession: PRJNA390547 ID: 390547

Human gammaherpesvirus 8

Identification of symmetric methylation of histone H4 arginine 3 on KSHV genome (H4R3me2s ChIP-Seq)

The objective of this study was to identify the symmetric methylation sites on KSHV genome during latency and lytic reactivation Overall design: KSHV infected, TRExBCBL1-RTA cells were induced with doxycycline for 12h to trigger the lytic reactivation, cells were crosslinked and subjected for chromatin isolation and sonication. More...
AccessionPRJNA390547; GEO: GSE100044
Data TypeEpigenomics
ScopeMultiisolate
OrganismHuman gammaherpesvirus 8[Taxonomy ID: 37296]
Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Gammaherpesvirinae; Rhadinovirus; Rhadinovirus humangamma8; Human gammaherpesvirus 8
PublicationsStrahan RC et al., "KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation.", PLoS Pathog, 2017 Jul;13(7):e1006482
SubmissionRegistration date: 14-Jun-2017
Verma Lab, Microbiology and Immunology, University of Nevada, Reno
RelevanceUnknown
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments8
Publications
PubMed1
PMC1
Other datasets
BioSample8
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Mbases52
Data volume, Mbytes15

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    Human gammaherpesvirus 8
    Identification of symmetric methylation of histone H4 arginine 3 on KSHV genome (H4R3me2s ChIP-Seq)
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