Mus musculus (ID 388933) - BioProject

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Accession: PRJNA388933 ID: 388933

Mus musculus (house mouse)

Reduced diploidization and survival improvement of semi-cloned mice produced from androgenetic haploid embryonic stem cells

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71617 additional projects are related by organism.

We found that the overall DNA methylation and hydroxymethylation in AG-haESCs are extremely low, and the downregulation of both de novo methyltransferase Dnmt3b and methylation maintenance enzyme Dnmt1was discovered responsible for this DNA hypomethylation. More...

Accession	PRJNA388933; GEO: GSE99588
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	He W et al., "Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b.", Stem Cell Reports, 2018 Feb 13;10(2):477-493
Submission	Registration date: 1-Jun-2017 Tongji University
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	6
Publications
PubMed	1
PMC	1
Other datasets
BioSample	6
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	18
Data volume, Mbytes	6483

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Mus musculus (house mouse)

Reduced diploidization and survival improvement of semi-cloned mice produced from androgenetic haploid embryonic stem cells

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