Mus musculus (ID 293894) - BioProject

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Accession: PRJNA293894 ID: 293894

Mus musculus (house mouse)

Gene expression profiling of control cohesin knockdown LSK cells

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This project is a component of the Loss of cohesin in vivo alters adult stem cell homeostasis leading to myeloproliferative neoplasms

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2 additional projects are components of the Loss of cohesin in vivo alters adult stem cell homeostasis leading to myeloproliferative neoplasms.

71557 additional projects are related by organism.

We performed RNA-sequencing in LSK cells (Lin(neg)/c-Kit(+)/Sca-1(+)) from shRNA mice carrying an shRNA for Renilla, Smc1a or Stag2. Overall design: RNA-sequencing control (Renilla) and cohesin (Smc1a and Stag2) knockdown cells.

Accession	PRJNA293894; GEO: GSE72369
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Mullenders J et al., "Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms.", J Exp Med, 2015 Oct 19;212(11):1833-50
Submission	Registration date: 25-Aug-2015 Aifantis, Pathology, NYU School of Medicine
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	10
Publications
PubMed	1
PMC	1
Other datasets
BioSample	10
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	20
Data volume, Mbytes	7355

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Mus musculus (house mouse)

Gene expression profiling of control cohesin knockdown LSK cells

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