Homo sapiens (ID 263155) - BioProject

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Accession: PRJNA263155 ID: 263155

Homo sapiens (human)

Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines

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We compared untreated HCC1419 cells with Lapatinib resistant HCC1419 cells that were either treated with Lapatinib for only 9 days before harvesting (drug tolerant persisters, DTPs) or were growing in the presence of Lapatinib (>70 days) (drug tolerant expanded persisters, DTEPs). More...

Accession	PRJNA263155; GEO: GSE62074
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Submission	Registration date: 6-Oct-2014 UCSC
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	7
Other datasets
BioSample	7
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	79
Data volume, Mbytes	68978

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Homo sapiens (human)

Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines

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