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Accession: PRJNA262735 ID: 262735

Homo sapiens (human)

Genome-wide maps of PARP-1-bound nucleosomes (human)

See Genome Information for Homo sapiens
PARP-1 binds to specific nucleosomes to regulate gene activity. While PARP-1's role in transcription inititaion is known, a surprising finding here was that PARP-1 is highly enriched at exon-intron and intron-exon boundaries, sort of demarcting exons. More...
AccessionPRJNA262735; GEO: GSE61916
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsNalabothula N et al., "Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation.", PLoS One, 2015;10(8):e0135410
SubmissionRegistration date: 30-Sep-2014
Mittendorf, Biochemistry, University of Kentucky
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments2
Publications
PubMed1
PMC1
Other datasets
BioSample2
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes43463
SRA Data Details
ParameterValue
Data volume, Gbases13
Data volume, Mbytes7621

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