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Genome Information for Mus musculus
We estimated differences of urethane-induced tumors between Nrf2+/+ and Nrf2-/- ICR mouse. To identify Nrf2-regulated genes in tumors, we examined the mRNA expression profile both in tumor and non-tumor tissue of mouse 4 months after urethane administration.
Overall design: We performed microarray analyses using the comparable size of lung tumors (1.0 mm < tumor diameter < 1.5 mm) and intact non-tumor lung tissues derived either from Nrf2+/+ (n=8) or Nrf2–/–mice (n=8) at 16-weeks after urethane(1-g/kg body weight) treatment.
| Accession | PRJNA197132; GEO: GSE46048 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Satoh H et al., "Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis.", Cancer Res, 2013 Jul 1;73(13):4158-68 |
| Submission | Registration date: 15-Apr-2013
Medical Biochemistry, Tohoku University Graduate School of Medicine |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 180072 |
| Data volume, Processed Mbytes | 3 |
| Data volume, Supplementary Mbytes | 9 |