CRISPR/Cas9 regulates EphA2-CDH1 axis to inhibit t... (ID 1111754) - BioProject

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Accession: PRJNA1111754 ID: 1111754

CRISPR/Cas9 regulates EphA2-CDH1 axis to inhibit the migration of castration-resistant prostate cancer cells (human)

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We ued CRISPR/Cas9 to knock out EphA2 gene in PC3 cells, and overexpress EphA2 gene in Du145 cells with overexpressed plasmids to explore the underlying mechanisms of EphA2 function in castration-resistant prostate cancer(CRPC) and clinical relevance, providing more evidence for EphA2 as a potential therapeutic target for CRPC. More...

Accession	PRJNA1111754; GEO: GSE267508
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Submission	Registration date: 15-May-2024 The Second Affiliated Hospital of Soochow University
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	8
Other datasets
BioSample	8
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	10

SRA Data Details

Parameter	Value
Data volume, Gbases	50
Data volume, Mbytes	15969

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CRISPR/Cas9 regulates EphA2-CDH1 axis to inhibit the migration of castration-resistant prostate cancer cells (human)

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