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Organizing biological data
A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells.
Drosophila melanogaster
GAGA-Associated Factor Mediates Long-Range Promoter-Promoter Connectivity
BMAL1-TTK-H2Bub1 loop deficiency contributes to impaired BM-MSC-mediated bone formation in senile osteoporosis
CFI-402257, a TTK inhibitor, effectively suppresses hepatocellular carcinoma
Candidate genes and pathways involved in TTK-induced biological functions in ovarian carcinoma
Camponotus floridanus raw sequencing reads 2021
Aneuploidy-induced sensitivity to spindle assembly checkpoint inhibition
Transcriptome profiling of Drosophila wild type and ttk-RNAi, dpn overexpressed, Nicd overexpressed and seq&Nicd overexpressed intestinal progenitor cells
Genome-wide DNA-binding analysis for Ttk in intestinal progenitor cells and Su(H) in wildtype, seq overexpressed and ttk-RNAi intestinal progenitor cells by DamID
RNAseq Study in CC-671 Treated Cal-51 Cells
We aim to stratify multifocal HCC and identify novel diagnostic and prognostic biomarkers by performing whole genome and transcriptome sequencing, as part of a multi-omics strategy.A complete collection of tumour and somatic specimens (intrahepatic HCC lesions, matched non-cancerous liver tissue and blood) were obtained from representative patients with multifocal HCC exhibiting two distinct postsurgical courses. Whole-genome and transcriptome sequencing with genotyping were performed for each tissue specimen to contrast genomic alterations, including hepatitis B virus integrations, somatic mutations, copy number variations, and structural variations.
Homo sapiens
Viral Expression and Molecular Profiling in Liver Tissue versus Microdissected Hepatocytes in Hepatitis B Virus - Associated Hepatocellular Carcinoma
Expression data of BRCA1 shRNA and PTEN shRNA single knockdown, BRCA1_PTEN shRNA double knockdowns and control shRNA in MCF-10A cells
Expression data of CHK1 shRNA knockdown and control shRNA in U2OS cells
Expression data of Brti1 shRNA knockdown and control shRNA in MCF-10A cells
Expression data of BRCA1 shRNA and Rad51 shRNA knockdown and control shRNA in MCF-10A cells
Expression data of ATM, ATR, CHK1, CHK2, and 53BP1 shRNA knockdown and control shRNA in MCF-10A cells
Expression data from wild type and ttk^twk mutant whole ovaries
Mis-expression of Tramtrack in Drosophila embryos
modENCODE_White Lab: genome-wide ChIP-chip and ChIP-Seq data
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