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Organizing biological data
Somito_RNASeq
Understanding the molecular basis of phenotypic variations in chickens is essential to elucidate how different breeds of these animals exhibit distinct characteristics, and it has important implications for avian genetic breeding programs. This study aimed to identify differences in gene expression and biological processes (BPs) between Brazilian broiler chicken (TT) and laying hen (CC) breeds, during early development (from 2.5 to 3.5 days), establishing the global transcriptional profile of the embryonic tissues that generate the wing and breast regions of the chicken. The TT and CC strains were selected at the National Center for Swine and Poultry Research of Embrapa.
Loss of CD4 T cell responses to prior vaccines associate with inflammation and altered transcriptional signatures in HIV infection
H3.3K122A results in a neomorphic phenotype in mouse embryonic stem cells (TT-Seq)
D. melanogaster tilt sequence
Thalassia testudinum strain:var. Tt-101
Thalassia testudinum strain:var. Tt-101 Raw sequence reads
Notch induces transcription by stimulating release of paused RNA Pol II without increasing chromatin accessibility [TT-seq]
Ubiquitylation of Pol II controls early stages of the transcription cycle [TT-seq]
KAP1 negatively regulates elongation kinetics to activate signal-induced transcription [TT-Seq]
Gene expression of ERAP2 proficient and deficient patient-derived organoids post IFNg-stimulation
Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis
An obesogenic FTO allele causes accelerated development, growth and insulin resistance in human skeletal muscle cells
ASH1L guards cis-regulatory elements against cyclobutane pyrimidine dimer induction [ChIP-seq]
Thalassia testudinum genome sequencing and assembly
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Transcription, RNA processing and RNA stability in T. brucei
Thalassia testudinum cultivar:Tt-101
Thalassia testudinum alternate haplotype genome sequencing and assembly
Thalassia testudinum main haplotype genome sequencing and assembly
Autophagy-enhancing ATG16L1 polymorphism improves clinical outcomes and promotes superior T-cell immunity in chronic HIV-1 infection
TT-seq in mESCs with and without TIP60
Farnesyltransferase inhibition overcomes the adaptive resistance to targeted therapies in oncogene-addicted non-small cell lung cancer II
Transcriptional shut-off of MAP kinase signaling enables pluripotency maintenance during diapause [PRO-seq]
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