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Items: 19

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1.

Porphyromonas gingivalis triggers microglia activation and neurodegenerative processes through NOX4

Organism:
Homo sapiens
Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
örebro University
Accession:
PRJNA1147160
ID:
1147160
2.

Spatial transcriptomics reveals an unexpected impact of tau and tau pathology on the expression of transthyretin

Spatial Transcriptomics analysis of transgenic mice (Alzheimer´s disease) reveal dysregulation of Ttr.

Project data type: Other
Scope:
Monoisolate
Science For Life Laboratory
Accession:
PRJEB75612
ID:
1135637
3.

Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1

Organism:
Homo sapiens
Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Young-Pearse, Neurology, Brigham and Womens Hospital
Accession:
PRJNA997371
ID:
997371
4.
5.

Modulation of the endocytic, bioenergetic and transcriptomic pathways subserve the neuroprotective, anti-amyloidogenic action of cleavage-specific tau 12A12mAb in Alzheimer Disease mouse model.

Project data type: Raw sequence reads
Scope:
Multispecies
Institute for Biomedical Research and Innovation CNR
Accession:
PRJNA925506
ID:
925506
6.

Neuronal Transcriptome Disruption, Tau Accumulation and Synapse Loss inAlzheimer’s Knock-in Mice Require Cellular Prion Protein

Organism:
Mus musculus
Taxonomy:
Mus musculus (house mouse)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Stephen Strimatter, Neurology, Yale University
Accession:
PRJNA915599
ID:
915599
7.

The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation

Organism:
Mus musculus
Taxonomy:
Mus musculus (house mouse)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Gladstone Institutes
Accession:
PRJNA901027
ID:
901027
8.

Human Tau Mutations in Cerebral Organoids Induce a Progressive Dyshomeostasis of Cholesterol

Organism:
Homo sapiens
Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Kenneth S. Kosik Laboratory, Neuroscience Research Institute, University of California Santa Barbara
Accession:
PRJNA859858
ID:
859858
9.

Glutamatergic dysfunction precedes neuron loss in cerebral organoids with MAPT mutations [bulk RNA-Seq]

Organism:
Homo sapiens
Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai
Accession:
PRJNA719235
ID:
719235
10.

The moringin/a-CD complex attenuates neuronal death and promotes cellular repair in an in vitro model of Alzheimer's disease: a transcriptomic study.

Project data type: Raw sequence reads
Scope:
Multispecies
IRCCS Centro Neurolesi "Bonino-Pulejo"
Accession:
PRJNA719033
ID:
719033
11.

Chronic intermittent hypoxia enhances pathological tau seeding, propagation, and accumulation, and exacerbates Alzheimer’s-like memory and synaptic plasticity deficits and molecular signatures

Organism:
Mus musculus
Taxonomy:
Mus musculus (house mouse)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Neuroscience, Icahn School of Medicine at Mount Sinai
Accession:
PRJNA716677
ID:
716677
12.

Good quality day 7 embryos display disturbed cellular functions during post-hatching development when oocytes were matured under lipotoxic conditions: novel insights from a bovine embryo-transfer model

Organism:
Bos taurus
Taxonomy:
Bos taurus (domestic cattle)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Gamete Research Centre, Veterinary Sciences, University of Antwerp
Accession:
PRJNA525706
ID:
525706
13.
14.

Homo sapiens

A novel hydrogel-based instructive biohybrid 3D culture system for modeling human neural stem cell plasticity, neurogenesis, neurodevelopment, and neurodegeneration

Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Columbia University Irving Medical Center
Accession:
PRJNA312638
ID:
312638
15.

Rattus norvegicus

Whole genome microarray gene expression profiling of hippocampal genes from aged rats subjected to chronic unpredictable mild stress

Taxonomy:
Rattus norvegicus (Norway rat)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Molecular Pharmacology, Swiss Federal Institute of Technology
Accession:
PRJNA292840
ID:
292840
16.

Mus musculus

A novel approach to Alzheimer’s Disease treatment: HDACs & PDE5 inhibition

Taxonomy:
Mus musculus (house mouse)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Unit of Proteomics, Genomics and Bioinformatics, FIMA
Accession:
PRJNA263566
ID:
263566
17.

Disease 2020: Large-Scale Sequencing and Analysis Center Initiated Projects/Baylor College of Medicine

Organism:
Homo sapiens
Taxonomy:
Homo sapiens (human)
Umbrella project (Subtype: Funding initiative)
Baylor College of Medicine
Accession:
PRJNA252586
ID:
252586
18.

Homo sapiens

Probing sporadic and familial Alzheimer?s disease using induced pluripotent stem cells.

Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Loring, Regenerative Medicine, The Scripps Research Institute
Accession:
PRJNA150093
ID:
150093
19.

Homo sapiens

Identification of Signature Molecule-Marked Native Mesenchymal Stem Cells

Taxonomy:
Homo sapiens (human)
Project data type: Transcriptome or Gene expression
Scope:
Multiisolate
Graduate School of Biomedical Sciences, Departments of Dental and Medical Biochemistry, Hiroshima University
Accession:
PRJNA103211
ID:
103211

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