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Accession: PRJNA646233 ID: 646233

Mus musculus strain:C57BL6 (house mouse)

Endothelial reprogramming by disturbed flow revealed by single-cell RNAseq and chromatin accessibility study

See Genome Information for Mus musculus

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71540 additional projects are related by organism.

Disturbed flow (d-flow) induces atherosclerosis by regulating gene expression in endothelial cells (ECs). More...

Accession	PRJNA646233
Data Type	Transcriptome or Gene expression, Epigenomics
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Andueza A et al., "Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study.", Cell Rep, 2020 Dec 15;33(11):108491
Grants	"Role of flow-sensitive KLK10 in endothelial dysfunction and atherosclerosis" (Grant ID R01 HL139757, National Heart, Lung, and Blood Institute) "Shear stress, endothelial miRNAs, and AV calcification" (Grant ID R01 HL119798, National Heart, Lung, and Blood Institute) "Anti-atherogenic and anti-inflammatory role of Bone Morphogenic Protein Receptor II" (Grant ID P01 HL095070, National Heart, Lung, and Blood Institute) "Georgia CTSA Research Supplement to Promote Diversity in Health-Related Research (Dunn)" (Grant ID UL1 TR002378, National Center for Advancing Translational Sciences)
Submission	Registration date: 14-Jul-2020 Emory University
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	16
Publications
PubMed	1
PMC	1
Other datasets
BioSample	4

SRA Data Details

Parameter	Value
Data volume, Gbases	239
Data volume, Tbytes	0.10

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Mus musculus strain:C57BL6
Mus musculus strain:C57BL6
Endothelial reprogramming by disturbed flow revealed by single-cell RNAseq and chromatin accessibility study

BioProject
PRJNA646233 (1)
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