BioProject

To better understand how males shorten the lifespan of the opposite sex in C. More...

To better understand how males shorten the lifespan of the opposite sex in C. elegans, we performed bulk RNA-seq to identify the hermaphrodite response to sexual interactions with males. To avoid confounds from embryo transcripts, we used sterile, glp-1 hermaphrodites which are susceptible to male-induced demise. We tested different ages of hermaphrodites (young, day 3 of life and older, day 7 of life) as well as different lengths of sexual interaction (1 day versus 5 days). Age-matched hermaphrodites that never experienced a sexual interaction with males were also used for RNA-seq. Less...