BioProject

To study human basic biology and disease, high-quality, error-free, complete genome assemblies are needed. More...

To study human basic biology and disease, high-quality, error-free, complete genome assemblies are needed. For this purpose, a trio of samples of a son and parents were collected to generate a high-quality, haplotype phased, reference genome as part of the G10K-VGP (Vertebrate Genomes Project). PacBio long reads were conducted at Pacific BioSciences and the Rockefeller University Vertebrate Genomes Lab (VGL) led by Olivier Fedrigo, Bionano optical maps and 10X Genomics libraries at the VGL, HiC at Arima Genomics, all on the son; shot gun illumina reads were generated on the parents by Adam Phillippy at NIH. Genome assembly was conducted by Arang Rhie, using the VGP 1.6 trio pipeline. This allowed assembly of both the paternal and maternal haplotype as chromosomes. The raw data and assembly are currently under a G10K-VGP publication embargo until removed from this description, following the G10K data use policy at the following URL: https://genome10k.soe.ucsc.edu/data-use-policies/ Less...