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Organizing biological data
Timing matters: Late, but not early, exercise training ameliorates MASLD in part by modulating the gut-liver axis in mice
While exercise is generally beneficial for the amelioration of Metabolic dysfunction-associated steatotic liver disease (MASLD), little is known about the best timing of exercise. Here we demonstrate in APOE*3-Leiden.CETP mice, an MASLD model, that specifically late, but not early, active period aerobic exercise leads to fat loss, amelioration of MASLD development and lower liver lipids. These changes coincide with a change in the gut microbiota composition of only late exercising mice towards a short-chain fatty acids producing profile. A fecal microbiota transplantation from late exercising mice to sedentary mice has partially reproduced MASLD-ameliorating effects of late exercise, depending on the success of the transplantation. These findings demonstrate the importance of the timing when conducting lifestyle interventions and lay a foundation for future clinical trials which can be used to adapt clinical guidelines for MASLD treatment.
Transcriptional response of the cacao pathogen Moniliophthora perniciosa to a strobilurin fungicide
CIRCLES-PIG
Impact of Diverse Farming Conditions and Nutritional Interventions on Swine Gut Microbiota
AKN
Oxygen-dependent dynamics of metformin dissipation at the sediment-water interface and their effects on prokaryotic communities
Limosilactobacillus fermentum strain:SLAM216 | isolate:Korean infant feces sample
Limosilactobacillus fermentum strain:SLAM216 | isolate:Korean infant feces sample Genome sequencing
Efficient implementation of anammox in an ultra-short hydraulic retention time anaerobic/oxic process for nutrient removal and resource recovery from sewage
Dietary iron attenuates Clostridioides difficile infection via modulating intestinal immune response and gut microbiota
RNA-seq from the hypothalamic medio-basal region of a male quail
Quail HMB RNA-seq
Cell-autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment
RNA seq of a novel Escherichia coli K-12 MG1655 L-form strain
Comparison of iPSC-derived human intestinal epithelial cells with Caco-2 cells and human in vivo data after exposure to Lactiplantibacillus plantarum WCFS1
Genome sequences of a novel Escherichia coli K-12 MG1655 L-form strain and its evolved variant
Effects of Season, Host Species and Origin of Antimicrobial Resistance in seabirds from the Southeast Pacific Coast
ESBL-E. coli prevalence in seabirds from the Southeast Pacific Coast
Liasis olivaceus (olive python) genome, rLiaOli1, sequence data
MAVS signaling shapes microglia responses to neurotropic virus infection
Time-course scRNA-seq of definitive endoderm directed differentiation
Lophira alata
Forensic tracing of tropical timber: delivering an operational service
RNAseq of E.coli ATCC 25922 +/- L-tryptophan.
L-tryptophan and copper interactions linked to reduced colibactin genotoxicity in pks+ Escherichia coli
L-rhamnose globally changes the transcriptome of planktonic and biofilm Escherichia coli cells and modulates biofilm growth
Transcriptome Responses to Different Nitrogen Levels Reveals Regulatory Networks for Icariin-Flavonoid Metabolism in Epimedium pubescens
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