PREVention of diabetes through lifestyle Intervention and population studies in Europe and around the World (PREVIEW) comprised a multi-centre, 3-year lifestyle intervention in overweight adults with pre-diabetes conducted in 8 countries, that aimed to decrease the incidence of T2D. In the present study, we study the gut microbiota from a subset of participants who followed an 8-week total meal replacement low-energy diet (LED) in the PREVIEW trial, from Finland and New Zealand (N=211), by Illumina sequencing of the 16S rRNA gene. We aimed to track changes in the composition and function of the gut microbiota during LED-induced weight loss, and to determine whether baseline microbiota configuration is associated with host metabolic response to the LED.
- Project data type: Other
- Scope:
- Monoisolate
- UNIVERSITY OF HELSINKI