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Organizing biological data
Somito_RNASeq
Understanding the molecular basis of phenotypic variations in chickens is essential to elucidate how different breeds of these animals exhibit distinct characteristics, and it has important implications for avian genetic breeding programs. This study aimed to identify differences in gene expression and biological processes (BPs) between Brazilian broiler chicken (TT) and laying hen (CC) breeds, during early development (from 2.5 to 3.5 days), establishing the global transcriptional profile of the embryonic tissues that generate the wing and breast regions of the chicken. The TT and CC strains were selected at the National Center for Swine and Poultry Research of Embrapa.
Homocysteine promotes the pathogenesis of atherosclerosis through circ-PIAS1-5/miR-219a-2-3p/TEAD1 axis
scRNAseq of spr-5; met-2 mutant embryos
Alternate-day fasting and the 5:2 diet alleviate distal symmetric polyneuropathy by regulating gut microbiota and metabolites
RNA-seq of human Caco-2 cells treated with a nutraceutical formula (solution-3), or vehicle-(saline solution)- control, and infected with SARS-CoV-2 (EG.5)
scRNA-seq, V(D)J seq, CITE-seq, LIBRA-seq of human CD4+, CD8+ and B lymphocytes PBMCs of 5 donors (3 SARS-CoV-2 experienced and 2 SARS-Cov-2 Naive) before and following two doses of Pfizer/BioNTech BNT162b2 mRNA vaccine
Pantoea brenneri strain:3.5.2
Pantoea brenneri strain:3.5.2 Genome sequencing
5-Aza-4'-thio-2'-deoxycytidine induces C>G transversions in a specific trinucleotide context and leads to acute lymphoid leukemia: mouse Exome sequencing data
5-Aza-4'-thio-2'-deoxycytidine induces C>G transversions in a specific trinucleotide context and leads to acute lymphoid leukemia: human cell line Exome sequencing data
A 5:2 intermittent fasting regimen initiated in the active phase ameliorates NASH, fibrosis and blunts HCC development via hepatic PPARα and PCK1
Six1 regulates mouse lower incisor development by coordinating Dlx1/2/5 [scRNA-seq]
Six1 regulates mouse lower incisor development by coordinating Dlx1/2/5 [CUT&Tag]
Mus musculus
Single-cell RNA sequencing of mouse uteri at 2.5, 3.5, 4.5, and 4.5dpp
Single-cell RNA sequencing of mouse uteri at 2.5, 3.5, 4.5, and 4.5dpc
Transcriptional profiling of CD11b+ microglia isolated from cerebellum and olfactory bulb-removed brains of SAMP8 and SAMR1 mice at 2, 5, and 9 months of age.
Probiotic-enriched oily suspension in modulating skin microbiome and treating seborrheic dermatitis
Seborrheic dermatitis (SD) is a skin condition affecting 2-5% of the global population, with skin microbiome imbalances playing a role in its onset. This research investigated the effects of EUTOPLAC, an oily suspension with Lactobacillus crispatus P17631 and Lacticaseibacillus paracasei I1688, on SD symptoms and the skin's microbial balance. 25 patients underwent a week-long EUTOPLAC treatment. Assessments taken at the baseline, after a week, and three weeks later showed symptom relief and a marked decline in the Malassezia genus. Additionally, a decrease in Staphylococcus and a rise in Lactobacillus and Lacticaseibacillus were observed. The study underscores EUTOPLAC's potential in SD treatment, both in symptom alleviation and microbiome modulation.
Recombinant SARS-CoV-2 delta/omicron BA.5 in Norway
Recombinant SARS-CoV-2 delta/omicron BA.5 emerging in a long-term infected COVID-19 patient
Metaranscriptomes of the Lake Baikal (fraction 0.2-5 um)
bioreactor metagenome
Biomass microbial communities from CSTR bioreactor in University of Wisconsin, Madison, WI, USA - KW_UFMP1.5_week20.2 metagenome
Biomass microbial communities from CSTR bioreactor in University of Wisconsin, Madison, WI, USA - KW_UFMP2.5_week20.2 metagenome
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