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Accession: PRJNA996635 ID: 996635

The influence of TFEB on gene expression in primary murine germinal center and non-germinal center B cells (house mouse)

See Genome Information for Mus musculus
To investigate TFEB-dependent mRNA expression in murine B cells, FACS-sorted germinal center and non-germinal center B lymphocytes of B-cell-specific conditional TFEB KO mice and control littermates were subjected to RNA sequencing analysis Overall design: Comparative gene expression profiling analysis of RNA-seq data for FACS-sorted germinal center (CD19+GL7+CD95+) and non-germinal center (CD19+GL7-CD95-) B cells of conditional TFEB KO mice (Tfeb fl/fl Mb1-Cre +/-) and control littermates (Tfeb fl/fl Mb1-Cre -/-)
AccessionPRJNA996635; GEO: GSE237799
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsMünchhalfen M et al., "TFEB activation hallmarks antigenic experience of B lymphocytes and directs germinal center fate decisions.", Nat Commun, 2024 Aug 14;15(1):6971
SubmissionRegistration date: 19-Jul-2023
NGS Integrative Genomics, Department of Pathology, Universitaetsmedizin Goettingen
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments21
Publications
PubMed1
PMC1
Other datasets
BioSample21
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes53
SRA Data Details
ParameterValue
Data volume, Gbases60
Data volume, Mbytes21805

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