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Accession: PRJNA975849 ID: 975849

RNA-sequencing of ERBB3hi and ERBB3lo breast luminal progenitor cells from n=3 premenopausal BRCA2 mutation carriers and n=5 non-carriers [RNASeq_3_ERBB3] (human)

See Genome Information for Homo sapiens
RNA-sequencing was performed on patient luminal progenitor breast cell subsets from premenopausal, preneoplastic BRCA2 mutation carriers and non-carriers to interrogate early transcriptional alterations in BRCA2mut/+ cells. More...
AccessionPRJNA975849; GEO: GSE233309
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsJoyce R et al., "Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers.", Nat Cell Biol, 2024 Jan;26(1):138-152
SubmissionRegistration date: 24-May-2023
Chen, ACRF Cancer Biology and Stem Cells, Walter and Eliza Hall Institute of Medical Research
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4

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