Crnic Institute Human Trisome Project - Trisomy 21... (ID 956947) - BioProject

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Accession: PRJNA956947 ID: 956947

Crnic Institute Human Trisome Project - Trisomy 21 Model Atlas: PolyA RNA-seq from C57BL/6 and Dp16 adult mouse brain tissue ± JAK1/2 inhibition with baricitinib (house mouse)

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Analysis of steady-state mRNA levels in adult mouse brain tissue at 7-11 weeks from wild-type C57BL/6 and Dp16 mice ± treatment with the JAK1/2 inhibitor baricitinib. More...

Accession	PRJNA956947; GEO: GSE229997
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Galbraith MD et al., "Multidimensional definition of the interferonopathy of Down syndrome and its response to JAK inhibition.", Sci Adv, 2023 Jun 28;9(26):eadg6218
Submission	Registration date: 18-Apr-2023 Pharmacology & Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	12
Publications
PubMed	1
PMC	1
Other datasets
BioSample	12
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	5

SRA Data Details

Parameter	Value
Data volume, Gbases	199
Data volume, Mbytes	66862

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Crnic Institute Human Trisome Project - Trisomy 21 Model Atlas: PolyA RNA-seq from C57BL/6 and Dp16 adult mouse brain tissue ± JAK1/2 inhibition with baricitinib (house mouse)

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