RNA-seq data for H-23 and H-358 parental and sotor... (ID 952670) - BioProject

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Accession: PRJNA952670 ID: 952670

RNA-seq data for H-23 and H-358 parental and sotorasib-resistant lines (human)

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This project is a component of the An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance

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4 additional projects are components of the An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance.

95277 additional projects are related by organism.

We measured gene expression using RNA-sequencing for two cell lines (H-23 and H-358) parental and their sotorasib-resistant equivalent without treatment or treated with with G12C KRAS inhibitor sotorasib (AMG510) Overall design: Expression profiling by high throughput sequencing

Accession	PRJNA952670; GEO: GSE229070
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Submission	Registration date: 5-Apr-2023 Genentech
Relevance	Medical

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	15
Other datasets
BioSample	15
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	69
Data volume, Mbytes	22466

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RNA-seq data for H-23 and H-358 parental and sotorasib-resistant lines (human)

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