ALKBH5-mediated m6A modification of 5-HT3A mRNA in... (ID 942619) - BioProject

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Accession: PRJNA942619 ID: 942619

ALKBH5-mediated m6A modification of 5-HT3A mRNA in primary sensory neurons promotes neuropathic pain behaviors (Norway rat)

See Genome Information for Rattus norvegicus

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5755 additional projects are related by organism.

trigeminal-mediated nerve injury increases the expression of the m6A demethylase ALKBH5 in the injured TG, which elevates the level of 5-HT3A in TG and induces pain-related behaviors. More...

Accession	PRJNA942619; GEO: GSE226989
Scope	Multiisolate
Organism	Rattus norvegicus[Taxonomy ID: 10116] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus
Publications	Huang Z et al., "FOXD3-mediated transactivation of ALKBH5 promotes neuropathic pain via m(6)A-dependent stabilization of 5-HT3A mRNA in sensory neurons.", Proc Natl Acad Sci U S A, 2024 Feb 6;121(6):e2312861121
Submission	Registration date: 9-Mar-2023 Physiology and Neurobiology, Soochow University
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	12
Publications
PubMed	1
PMC	1
Other datasets
BioSample	12
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	18

SRA Data Details

Parameter	Value
Data volume, Gbases	95
Data volume, Mbytes	34835

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ALKBH5-mediated m6A modification of 5-HT3A mRNA in primary sensory neurons promotes neuropathic pain behaviors (Norway rat)

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