We investigated antigen-specific avoidance behavior in mice, and found that is critically dependent on mast cells.
We analyzed gene expression comparing naive versus immunized wild type mice, and versus mast cell-deficient mice at different times following antigen exposure.
This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA933616; GEO: GSE225054 |
| Type | Umbrella project |
| Publications | Plum T et al., "Mast cells link immune sensing to antigen-avoidance behaviour.", Nature, 2023 Aug;620(7974):634-642 |
| Submission | Registration date: 10-Feb-2023
Cellular Immunology, Immunology, German Cancer Research Center |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 91 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 91 |
| GEO DataSets | 3 |
Mast cells link immune sensing to antigen avoidance behavior encompasses the following 2 sub-projects:
| Project Type | Number of Projects |
| Transcriptome or Gene expression | 2 |
BioProject
accession | Organism | Title |
|---|
| PRJNA934580 | Mus musculus | Mast cells link immune sensing to antigen avoidance behavior [stomach] (Cellular Immunology, Immunology,...) | | PRJNA933010 | Mus musculus | Mast cells link immune sensing to antigen avoidance behavior [intestine] (Cellular Immunology, Immunology,...) |
|