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Accession: PRJNA886399 ID: 886399

Aurora A Kinase Inhibition Induces Accumulation of Tumor Cells in Mitosis with Restored Interferon Signaling to Potentiate Response to PD-L1 Immune Checkpoint Blockade

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA886399; GEO: GSE214614
TypeUmbrella project
PublicationsLi Y et al., "Aurora A kinase inhibition induces accumulation of SCLC tumor cells in mitosis with restored interferon signaling to increase response to PD-L1.", Cell Rep Med, 2023 Nov 21;4(11):101282
SubmissionRegistration date: 2-Oct-2022
Dana-Farber Cancer Institute
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments14
Publications
PubMed1
PMC1
Other datasets
BioSample14
GEO DataSets3
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes442
SRA Data Details
ParameterValue
Data volume, Gbases163
Data volume, Mbytes52515
Aurora A Kinase Inhibition Induces Accumulation of Tumor Cells in Mitosis with Restored Interferon Signaling to Potentiate Response to PD-L1 Immune Checkpoint Blockade encompasses the following 2 sub-projects:
Project TypeNumber of Projects
Transcriptome or Gene expression2
BioProject
accession
OrganismTitle
PRJNA886400Mus musculusAurora A Kinase Inhibition Induces Accumulation of Tumor Cells in Mitosis with Restored Interferon Signaling to Potentiate Response to PD-L1 Immune Checkpoint Blockade [RNA-seq] (Dana-Farber Cancer Institute)
PRJNA885505Mus musculusAurora A Kinase Inhibition Induces Accumulation of Tumor Cells in Mitosis with Restored Interferon Signaling to Potentiate Response to PD-L1 Immune Checkpoint Blockade [single cell RNA-seq] (Dana-Farber Cancer Institute)

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