BioProject

To investigate the changes in gene expression during the process of differentiation into neutrophils and to evaluate the effect of Ak2 hetero-knockout in the process, microarray analysis was performed. More...

To investigate the changes in gene expression during the process of differentiation into neutrophils and to evaluate the effect of Ak2 hetero-knockout in the process, microarray analysis was performed. HL-60 Ak2 hetero-knockout clone #47 cells were cultured with all-trans retinoic acid (ATRA) for 4 days. The cells were collected at four different time points and total RNA was prepared for use as a sample for microarray analysis. Overall design: HL-60 Ak2 hetero-knockout clone #47 cells were cultured with 10 µM ATRA and were collected at Day 0, 1, 2, and 4. Using prepared total RNA at each time point, microarray analysis was performed. Less...