Dyrk1a dosage effects on the transcriptome of embr... (ID 804912) - BioProject

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Accession: PRJNA804912 ID: 804912

Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using scRNAseq (house mouse)

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This project is a component of the Down Syndrome

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4 additional projects are components of the Down Syndrome.

We performed single cell RNAseq on whole hearts from E13.5 Dp1Tyb embryos and from wild-type littermates, as well as hearts from E13. More...

Accession	PRJNA804912; GEO: GSE196446
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Lana-Elola E et al., "Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome.", Sci Transl Med, 2024 Jan 24;16(731):eadd6883
Submission	Registration date: 9-Feb-2022 Francis Crick Institute
Relevance	Model Organism

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	39

Parameter	Value
Data volume, Gbases	258
Data volume, Tbytes	0.14

Supplemental Content

Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb m...
Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using scRNAseq
Dyrk1a dosage effects on the transcriptome of embryonic hearts from the Dp1Tyb mouse model of Down syndrome using scRNAseq

BioProject
RecName: Full=Zinc finger FYVE domain-containing protein 9; AltName: Full=Mother...
RecName: Full=Zinc finger FYVE domain-containing protein 9; AltName: Full=Mothers against decapentaplegic homolog-interacting protein; Short=Madh-interacting protein; AltName: Full=Novel serine protease; Short=NSP; AltName: Full=Receptor activation anchor; Short=hSARA; AltName: Full=Smad anchor for receptor activation
gi|15214067|sp|O95405.2|ZFYV9_HUMAN

Protein
Proteins for Structure (Select 20990) (2)
Protein
Related gene-specific medical variations for Gene (Select 254028) (5)
ClinVar
Taxonomy Links for Protein (Select 768014719) (1)
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