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Accession: PRJNA787702 ID: 787702

Rapid Acceleration of Diagnostics - Radical (RADx-rad): Improved Scalability, Sensitivity, and Interpretability of Pathogen Detection, Including SARS-CoV-2, in Wastewater using High-Throughput, Highly Multiplexed Digital Array PCR Technology (human)

See Genome Information for Homo sapiens
Presently, the application of molecular technologies, such as, RT-qPCR and digital PCR (dPCR) to quantify SARS-CoV-2 and related targets in wastewater is cumbersome, time consuming, and costly. While progress has been made in the development of methods and in the interpretation of data, much remains to be improved for the technology to be used as a public health management tool. A major drawback in the current approaches are: 1) the lack of streamlined and consistent pre-analytical processing steps, 2) coverage across the relevant targets requires a high number of reactions (>20) from any singe sample to provide quantitative information, and 3) a lack of vision of the development of a pathogen/marker panel, much like those used in clinical arenas, for the interpretation of data... (for more see dbGaP study page.)
AccessionPRJNA787702; dbGaP: phs002729
TypeUmbrella project (Subtype:Authorized Access)
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
SubmissionRegistration date: 9-Dec-2021
OD
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Genotype and Phenotype (dbGaP)1
Rapid Acceleration of Diagnostics - Radical (RADx-rad): Improved Scalability, Sensitivity, and Interpretability of Pathogen Detection, Including SARS-CoV-2, in Wastewater using High-Throughput, Highly Multiplexed Digital Array PCR Technology encompasses the following sub-project:
Project TypeNumber of Projects
Phenotype or Genotype1
BioProject
accession
OrganismTitle
PRJNA787703Homo sapiensRapid Acceleration of Diagnostics - Radical (RADx-rad): Improved Scalability, Sensitivity, and Interpretability of Pathogen Detection, Including SARS-CoV-2, in Wastewater using High-Throughput, Highly Multiplexed Digital Array PCR Technology (UNC Chapel Hill)

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  • Rapid Acceleration of Diagnostics - Radical (RADx-rad): Improved Scalability, S...
    Rapid Acceleration of Diagnostics - Radical (RADx-rad): Improved Scalability, Sensitivity, and Interpretability of Pathogen Detection, Including SARS-CoV-2, in Wastewater using High-Throughput, Highly Multiplexed Digital Array PCR Technology
    Rapid Acceleration of Diagnostics - Radical (RADx-rad): Improved Scalability, Sensitivity, and Interpretability of Pathogen Detection, Including SARS-CoV-2, in Wastewater using High-Throughput, Highly Multiplexed Digital Array PCR Technology
    BioProject

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