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Accession: PRJNA746323 ID: 746323

Bruton’s tyrosine kinase (BTK) and indoleamine 2,3-dioxygenase (IDO) block differentiation of inflammatory dendritic cells in tumors

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA746323; GEO: GSE180039
TypeUmbrella project
PublicationsSharma MD et al., "Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity.", Immunity, 2021 Oct 12;54(10):2354-2371.e8
SubmissionRegistration date: 13-Jul-2021
2125 K, Georgia Cancer Center, Augusta University
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments10
Publications
PubMed1
PMC1
Other datasets
BioSample10
GEO DataSets4
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes899
SRA Data Details
ParameterValue
Data volume, Gbases235
Data volume, Mbytes97463
Bruton’s tyrosine kinase (BTK) and indoleamine 2,3-dioxygenase (IDO) block differentiation of inflammatory dendritic cells in tumors encompasses the following 3 sub-projects:
Project TypeNumber of Projects
Epigenomics1
BioProject
accession
OrganismTitle
PRJNA746298Mus musculusBruton’s tyrosine kinase (BTK) and indoleamine 2,3-dioxygenase (IDO) block differentiation of inflammatory dendritic cells in tumors [ATAC-seq] (2125 K, Georgia Cancer Center,...)
Transcriptome or Gene expression2
BioProject
accession
OrganismTitle
PRJNA746405Mus musculusBruton’s tyrosine kinase (BTK) and indoleamine 2,3-dioxygenase (IDO) block differentiation of inflammatory dendritic cells in tumors [scRNA-seq] (2125 K, Georgia Cancer Center,...)
PRJNA746314Mus musculusBruton’s tyrosine kinase (BTK) and indoleamine 2,3-dioxygenase (IDO) block differentiation of inflammatory dendritic cells in tumors [Bulk RNA-seq] (2125 K, Georgia Cancer Center,...)

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