A genetic mouse model of malignant peripheral nerv... (ID 722488) - BioProject

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Accession: PRJNA722488 ID: 722488

A genetic mouse model of malignant peripheral nerve sheath tumor with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human tumors

We established a new genetically engineered mouse (GEM) model of malignant peripheral nerve sheath tumors (MPNST) based on postnatal deletion of a Nf1;Trp53 cis-conditional allele by the tamoxifen-inducible Plp-CreER (NP-Plp). More...

Accession	PRJNA722488; GEO: GSE172221
Data Type	Transcriptome or Gene expression
Scope	Multispecies
Publications	Inoue A et al., "A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor.", Neurooncol Adv, 2021 Jan-Dec;3(1):vdab129
Submission	Registration date: 16-Apr-2021 Center for Applied Bioinformatics, St Jude Children's Research Hospital
Relevance	Unknown

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	44
Publications
PubMed	1
PMC	1
Other datasets
BioSample	44
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	29

SRA Data Details

Parameter	Value
Data volume, Gbases	631
Data volume, Tbytes	0.10

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A genetic mouse model of malignant peripheral nerve sheath tumor with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human tumors

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