See
Genome Information for Homo sapiens
CRISPR knockout screening on MOLM-13 cells with KPT-9274
Overall design: MOLM-13 cells were transduced with geckov2 CRISPR knockout library (Addgene 1000000048 ) with: 1) baseline (7 days post library infection), 2) KPT-9274-treated, 3) DMSO control.
| Accession | PRJNA681917; GEO: GSE162473 |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Zhang P et al., "Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition.", Clin Cancer Res, 2021 Apr 15;27(8):2352-2366 |
| Submission | Registration date: 1-Dec-2020
Ohio State University |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 3 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 3 |
| GEO DataSets | 1 |