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Accession: PRJNA631746 ID: 631746

Memory-like HCV-specific CD8+ T cells retain a chronic scar after cure of chronic HCV infection (human)

See Genome Information for Homo sapiens
Investigation of phenotypical changes between exhausted HCV-specific CD8+ T cells during chronic infection and after DAA-mediated cure investigation of heterogeneity withhin the HCV-specific CD8+ T cell population Overall design: Single-cell RNA sequencing of HCV-specific CD8+ T cell subsets of 6 chronically infected patients during chronic HCV infection (n=6) and after DAA-mediated HCV cure targeting conserved (n=2).
AccessionPRJNA631746; GEO: GSE150305
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsHensel N et al., "Memory-like HCV-specific CD8(+) T cells retain a molecular scar after cure of chronic HCV infection.", Nat Immunol, 2021 Feb;22(2):229-239
SubmissionRegistration date: 11-May-2020
Sagar, Department of Internal Medicine II, University Medical Center Freiburg
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments26
Publications
PubMed1
Other datasets
BioSample26
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes6
SRA Data Details
ParameterValue
Data volume, Gbases33
Data volume, Mbytes15390

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