See
Genome Information for Mus musculus
Many lines of evidence suggest that poly(ADP-ribose) polymerase-1 (Parp-1) is involved in transcriptional regulation of various genes as a coactivator or a corepressor by modulating chromatin structure.
More...Many lines of evidence suggest that poly(ADP-ribose) polymerase-1 (Parp-1) is involved in transcriptional regulation of various genes as a coactivator or a corepressor by modulating chromatin structure. However, the impact of Parp-1-deficiency on the regulation of genome-wide gene expression has not been fully studied yet. We employed a microarray analysis covering 12,488 genes and ESTs using mouse Parp-1-deficient (Parp-1-/-) embryonic stem (ES) cell lines, primary embryonic fibroblasts (PMEF), and the livers of Parp-1-/- mice and their wild-type (Parp-1+/+) counterparts.
Less...| Accession | PRJDB7987 |
| Data Type | Transcriptome or Gene expression |
| Scope | Monoisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Ogino H et al., "Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells.", BMC Genomics, 2007 Feb 7;8:41 |
| Submission | Registration date: 4-Feb-2019
ADP-ribosylation in Oncology Project, National Cancer Center Research Institute |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
No public data is linked to this project. Any recently released data that cites this project will be linked to it within a few days.