Homo sapiens (ID 386496) - BioProject

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Accession: PRJNA386496 ID: 386496

Homo sapiens (human)

Epitope mapping of 5 monoclonal antibodies directed against meningococcal factor H binding protein by peptide microarray

See Genome Information for Homo sapiens

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This project is a component of the Epitope mapping of human antibodies directed against 4CmenB protein components

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3 additional projects are components of the Epitope mapping of human antibodies directed against 4CmenB protein components.

95323 additional projects are related by organism.

The aim of the study was to determine the epitope targeted by 5 different HumAbs and the cross-reactivity to linear peptide epitopes of 12 different factor H binding protein (fHbp) variants. More...

Accession	PRJNA386496; GEO: GSE98879
Data Type	Proteome
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Bianchi F et al., "Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6.", FASEB J, 2019 Nov;33(11):12099-12111 Giuliani M et al., "Human protective response induced by meningococcus B vaccine is mediated by the synergy of multiple bactericidal epitopes.", Sci Rep, 2018 Feb 27;8(1):3700
Submission	Registration date: 12-May-2017 Molecular Biology, AIMB, GSK Vaccines
Relevance	Medical

Project Data:

Resource Name	Number of Links
Publications
PubMed	2
PMC	2
Other datasets
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Spots	1815
Data volume, Processed Mbytes	1
Data volume, Supplementary Mbytes	1

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Homo sapiens (human)

Epitope mapping of 5 monoclonal antibodies directed against meningococcal factor H binding protein by peptide microarray

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