BioProject

The environmental human fungal pathogen, Cryptococcus neoformans, undergoes morphological and transcriptional adaptation in the switch from comensialism to pathogenicity. More...

The environmental human fungal pathogen, Cryptococcus neoformans, undergoes morphological and transcriptional adaptation in the switch from comensialism to pathogenicity. Here we have investigated pheromone-independent filamentation. Relative to wild type strain, transcript profiling of MAT2 deletion mutants on media with copper revealed that pheromone is not essential for filamentation under this condition. Overall design: Strand specific RNA-seq comparing transcrip profiling of mat△ strains to the respective wildtype strain XL280 on copper media. Less...