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Accession: PRJNA1139793 ID: 1139793

Basal-to-inflammatory transition enhances basal cell carcinoma (BCC) therapy resistance via crosstalk with a pro-inflammatory stromal niche [RNA-seq II] (house mouse)

See Genome Information for Mus musculus
The goal of these RNA-seq experiments was to determine transcriptomic gene expression changes caused by 7 days of Il1a and Osm combination treatment of mouse primary BCC tumor-derived organoids compared to PBS control Overall design: Mouse primary BCC tumor tissues were embedded as small pieces in basement membrane extract and grown in organoid medium for 7 days. More...
AccessionPRJNA1139793; GEO: GSE273014
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLi NY et al., "Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche.", Nat Commun, 2024 Sep 17;15(1):8134
SubmissionRegistration date: 24-Jul-2024
Dermatology, Stanford University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
PMC1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases24
Data volume, Mbytes6805

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