We performed deep mutational scanning of influenza H3 HA from strains A/HongKong/45/2019 and A/Perth/16/2009 to map mutations that escape neutralization by human serum. This analysis was conducted using sera from different age cohorts and geographic locations.
| Accession | PRJNA1124381 |
| Data Type | Raw sequence reads |
| Scope | Multispecies |
| Publications | - Published online: Welsh F et al., "Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin", bioRxiv, 2023;
|
| Grants | - "Contract, awarded by NIAID" (Grant ID 75N93021C00015, National Institute of Allergy and Infectious Diseases Extramural Activities)
- "Forecasting influenza evolution on a heterogeneous immune landscape" (Grant ID R01 AI165821, National Institute of Allergy and Infectious Diseases Extramural Activities)
|
| Submission | Registration date: 15-Jun-2024
Fred Hutchinson Cancer Center |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 289 |
| Other datasets |
| BioSample | 3 |