See
Genome Information for Homo sapiens
Three potential off-target sites for each gRNA were identified by CRISPOR (http://crispor.
More...Three potential off-target sites for each gRNA were identified by CRISPOR (http://crispor.org) based on the protospacer adjacent motif (PAM) sequence in the hg38 reference genome and a high mitOfftargetScore. Off-target editing frequencies in HEK293FT cells were measured by targeted amplicon sequencing.
Less...| Accession | PRJDB18094 |
| Data Type | Targeted Locus (Loci) |
| Scope | Monoisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | - Published online: Kato-Inui T et al., "Fusion of histone variants to Cas9 suppresses non-homologous end joining", PLOS ONE, 2024;19(5)
|
| Grants | - N/A, Uehara Memorial Foundation
- N/A, Takeda Science Foundation
- "KAKENHI" (Grant ID 17H04993, Japan Society for the Promotion of Science)
- "KAKENHI" (Grant ID 19K06631, Japan Society for the Promotion of Science)
- "KAKENHI" (Grant ID 20H03442, Japan Society for the Promotion of Science)
|
| Submission | Registration date: 15-May-2024
Regenerative Medicine Project, Tokyo Medical Institute of Medical Science |
| Related Resources | |
Project Data:
No public data is linked to this project. Any recently released data that cites this project will be linked to it within a few days.