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Genome Information for Bacillus subtilis
Antimicrobial peptides (AMPs) are instrumental in the maintenance of intestinal homeostasis and have emerged as potential therapeutic candidates for the amelioration of intestinal bacterial infections.
More...Antimicrobial peptides (AMPs) are instrumental in the maintenance of intestinal homeostasis and have emerged as potential therapeutic candidates for the amelioration of intestinal bacterial infections. However, the intrinsic instability associated with the in vivo delivery of AMPs constitutes a substantial impediment to their therapeutic efficacy in addressing infections. In this study, we genetically modified Bacillus subtilis WB600 to express Zophobas atratus defensin (Z. atratus defensing, ZD), an antimicrobial peptide (AMP) with broad-spectrum activity isolated from Zophobas atratus, for oral administration.
Less...| Accession | PRJNA1107689 |
| Data Type | Genome sequencing and assembly, Raw sequence reads, Genome sequencing |
| Scope | Monoisolate |
| Organism | Bacillus subtilis[Taxonomy ID: 1423] Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus; Bacillus subtilis |
| Submission | Registration date: 4-May-2024
CHINA AGRICULTURE UNIVERSITY |
| Locus Tag Prefix | AA5L35 |
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