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Accession: PRJNA1105321 ID: 1105321

CRL4-DCAF15 control of cohesin dynamics sustains cell proliferation [RNA-seq_dTAG] (human)

See Genome Information for Homo sapiens
The CRL4-DCAF15 E3 ubiquitin ligase complex is targeted by the aryl-sulfonamide molecular glues, leading to neo-substrate recruitment, ubiquitination, and proteasomal degradation. More...
AccessionPRJNA1105321; GEO: GSE266010
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsGrothusen GP et al., "DCAF15 control of cohesin dynamics sustains acute myeloid leukemia.", Nat Commun, 2024 Jul 3;15(1):5604
SubmissionRegistration date: 27-Apr-2024
Luca Busino Laboratory, Cancer Biology, University of Pennsylvania
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed1
PMC1
Other datasets
BioSample9
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases66
Data volume, Mbytes20157

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