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Genome Information for Mus musculus
GDE5/Gpcpd1 hydrolyzes Glycerophosphocholine (GPC) into choline and glycerol 3-phosphate.
More...GDE5/Gpcpd1 hydrolyzes Glycerophosphocholine (GPC) into choline and glycerol 3-phosphate. Skeletal muscle-specific GDE5 deletion showed reduced passive force and improved fatigue resistance in electrically stimulated gastrocnemius muscles. Metabolome analysis of GDE5-deficient muscles showed an altered profile, especially for glycolytic metabolites. Lipidome analysis of GDE5-deficient muscles also showed reduced levels of PC with highly polyunsaturated fatty acids such as DHA. A similar lipidome profile was observed in the skeletal muscles of denervated and Duchenne muscular dystrophy mouse models.
Less...| Accession | PRJDB17952 |
| Scope | Monoisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Submission | Registration date: 17-Apr-2024
Gunma university |
| Related Resources | |
Project Data:
| Resource Name | Number
of Links |
|---|
| BioSample | 39 |
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