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Genome Information for Homo sapiens
The global incidence of frozen shoulder (FS) and osteoporosis (OP) is high. Although FS patients may experience localized OP in the shoulder, there is still insufficient strong evidence to confirm the relationship between FS and OP.
More...The global incidence of frozen shoulder (FS) and osteoporosis (OP) is high. Although FS patients may experience localized OP in the shoulder, there is still insufficient strong evidence to confirm the relationship between FS and OP. The main objective of this current research is to investigate the pathogenesis mechanism of FS and explore the connection between FS and OP. We obtained FS and OP datasets from GEO and identified crosstalk genes. TAK715 was found to also intervene in the activation of osteoclasts. We successfully established a FS and OVX rat model, with the FS with OVX rat displaying more severe symptoms. Results demonstrated that TAK715 effectively corrected both fibrosis and osteoporosis simultaneously in vivo.
Less...| Accession | PRJNA1100765 |
| Data Type | Raw sequence reads |
| Scope | Monoisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Submission | Registration date: 16-Apr-2024
Sun Yat-sen Memorial Hospital |
| Relevance | Medical |
| Locus Tag Prefix | AAE266 |
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